C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/4545 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2657930
A process for making (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile and salts thereof, and intermediates used in the process are disclosed.
La présente invention concerne, d'une part un procédé de fabrication du (2S,5R)-5-éthynyl-1-{N-(4-méthyl-1-(4-carboxy-pyridin-2-yl)pipéridin-4-yl)glycyl}pyrrolidine-2-carbonitrile et de certains de ses sels, et d'autre part des intermédiaires utilisés pour ce procédé.
Bhagavatula Lakshmi
Borchardt Thomas B.
Engstrom Kenneth M.
Fickes Michael G.
Gandarilla Jorge
Abbott Laboratories
Torys Llp
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