Method for the preparation of citalopram

Details Method for the preparation of citalopram Method for the preparation of citalopram

C - Chemistry, Metallurgy

07

D

C07D 307/87 (2006.01) A61K 31/343 (2006.01)

Patent

CA 2400682

A method for the preparation of citalopram wherein the aldehyde of formula (II) is converted to the corresponding 5-cyano compound of formula (I) which is alkylated to form citalopram, which is isolated in the form of the base or an acid addition salt thereof.

L'invention concerne un procédé de préparation de citalopram dans lequel l'aldéhyde de formule (II) est transformée en composé 5-cyano correspondant de formule (I) qui, après alkylation, permet d'obtenir le citalopram. Le citalopram est isolé sous la forme base ou comme sel d'addition acide.

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