Urinary biomarkers for predicting long-term dialysis

G - Physics – 01 – N

Patent

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G01N 33/50 (2006.01) A61M 1/14 (2006.01)

Patent

CA 2737779

This invention is related to the field of the prevention and treatment of kidney disease. The treatment of kidney disease may be tailored depending upon the need for, or expectation of, long-term dialysis. For example, prediction of long-term dialysis treatment can be determined by monitoring urine biomarkers related to the development of chronic kidney disease. For example, a normalized time course of hyaluronic acid can be used to determine whether a patient having suffered acute kidney injury will require long-term dialysis.

L'invention concerne le domaine de la prévention et du traitement des maladies rénales. Le traitement des maladies rénales peut être personnalisé en fonction du besoin ou d'une dialyse probable longue durée. La prédiction d'un traitement de dialyse longue durée peut par exemple être déterminée par surveillance de biomarqueurs d'urine concernant le développement d'une maladie rénale chronique. Par exemple, on peut utiliser le décours temporel amélioré de l'acide hyaluronique pour déterminer si un patient souffrant d'une défaillance rénale aigüe nécessitera une dialyse longue durée.

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