Use of non-peptidyl compounds for the treatment of insulin...

Details Use of non-peptidyl compounds for the treatment of insulin... Use of non-peptidyl compounds for the treatment of insulin...

A - Human Necessities

61

K

A61K 38/28 (2006.01) A61K 31/00 (2006.01) A61K 31/18 (2006.01) A61K 31/185 (2006.01) A61K 31/19 (2006.01) A61K 31/192 (2006.01) A61K 31/255 (2006.01) A61K 31/35 (2006.01) A61K 31/352 (2006.01) A61K 31/353 (2006.01) A61K 31/4155 (2006.01) A61K 31/4709 (2006.01)

Patent

CA 2345155

The present invention relates to the use of at least a non-peptidyl compound as a biological modulator of insulin activity or insulin-related activity, which compound possesses ionic and hydrophobic chemical moieties spatially located so as to mimic at least an ionic and hydrophobic amino acid residue of insulin, which amino acids are associated with the binding of insulin to its receptor.

L'invention concerne l'utilisation d'au moins un composé non-peptidylique comme modulateur biologique de l'activité insulinique ou de l'activité liée à l'insuline. Ledit composé possède des parties chimiques ioniques et hydrophobes situées dans l'espace de sorte qu'elles imitent au moins un reste d'acide aminé ionique et hydrophobe de l'insuline, lesdits acides aminés étant associés à la fixation de l'insuline à son récepteur.

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