Compositions with modified nucleases targeted to viral...

Details Compositions with modified nucleases targeted to viral... Compositions with modified nucleases targeted to viral...

C - Chemistry, Metallurgy

12

N

C12N 9/22 (2006.01) A61K 38/46 (2006.01) C07H 21/04 (2006.01)

Patent

CA 2604243

Antiviral compositions comprising a modified nuclease, or a plurality of such modified nucleases having at least one non-natural amino acid residue substituted for a naturally occurring amino acid in a parent nuclease are provided, as are methods of use and kits providing unit dosages of such compositions.

La présente invention concerne des compositions antivirales comprenant une nucléase modifiée, ou une pluralité de ces nucléases modifiées comportant au moins un résidu d'acide aminé non naturel substitué par un acide aminé naturel dans une nucléase parente, ainsi que des méthodes d'utilisation de ces compositions et des trousses fournissant des doses uniques de ces compositions.

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