A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/715 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) C07H 11/00 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) C07K 14/50 (2006.01) C07K 14/52 (2006.01) C07K 14/54 (2006.01) C08B 37/00 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2157388
Disclosed are: (1) methods for identifying natural and synthetic sequences having binding specificity for glycan-binding proteins, including proteins that act as effectors of biological activity, (2) compositions and methods of producing protein-specific glycosaminoglycan sequence and ligand antagonists capable of modulating the effector function of these ligands, and teherapautic compositions comprising these antagonists; and (3) compositions and methods for producing protein-spedific glycosaminoglycan sequence analogs useful as agonists, and therapeutic compositions comprising these agonists.
Divulgation : (1) de méthodes d'identification de séquences naturelles et synthétiques ayant une spécificité de liaison avec les protéines liant les glycanes, y compris des protéines qui agissent comme effecteurs de l'activité biologique, (2) de compositions et de méthodes de production de séquence de glycosaminoglycane spécifique aux protéines et d'antagonistes de ligands capables de moduler la fonction effecteur de ces ligands et de compositions thérapeutiques comprenant ces antagonistes; et (3) de compositions et de méthodes pour la production d'analogues de la séquence de glycosaminoglycane spécifique aux protéines utiles comme agonistes, et de compositions thérapeutiques comprenant ces agonistes.
Herlihy Walter C. Jr.
Witt Daniel P.
Glycan Parmaceuticals Inc.
Riches Mckenzie & Herbert Llp
LandOfFree
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