C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07H 19/04 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01)
Patent
CA 2557818
This invention provides a method for determining the sequence of a DNA or an RNA, wherein (i) about 1000 or fewer copies of the DNA or RNA are bound to a solid substrate via 1,3-dipolar azide-alkyne cycloaddition chemistry and (ii) each copy of the DNA or RNA comprises a self-priming moiety.
L'invention concerne un procédé destiné à déterminer la séquence d'un ADN ou d'un ARN, dans lequel (i) environ 1000 ou moins de copies de l'ADN ou de l'ARN sont liés à un substrat solide via une chimie de cycloaddition d'azide-alkyne dipolaire 1,3 et (ii) chaque copie de l'ADN ou de l'ARN comprend une fraction à amorçage automatique.
Ju Jingyue
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
The Trustees Of Columbia University In The City Of New York
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