Tricyclic compounds as mrp1-inhibitors

Details Tricyclic compounds as mrp1-inhibitors Tricyclic compounds as mrp1-inhibitors

C - Chemistry, Metallurgy

07

D

C07D 498/04 (2006.01) A61K 31/435 (2006.01) A61K 31/4745 (2006.01) A61K 31/704 (2006.01) A61K 31/7048 (2006.01) A61K 45/06 (2006.01) A61P 35/00 (2006.01) C07D 221/00 (2006.01) C07D 261/00 (2006.01)

Patent

CA 2411813

The present invention relates to a compounds of formula I, wherein A is olefin, diol, or acetonide; which are useful for inhibiting resistant neoplasms where the resistance is conferred in part or in total by MRP1.

L'invention concerne des composés de formule (I), dans laquelle A désigne une oléfine, un diol ou un acétonide, qui sont utilisés pour l'inhibition de néoplasmes résistants, où la résistance est conférée en partie ou en totalité par MRP1.

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