Non-imidazole heterocyclic compounds

Details Non-imidazole heterocyclic compounds Non-imidazole heterocyclic compounds

C - Chemistry, Metallurgy

07

D

C07D 213/82 (2006.01) A61K 31/422 (2006.01) A61K 31/444 (2006.01) A61K 31/497 (2006.01) A61P 25/00 (2006.01) A61P 37/08 (2006.01) C07D 213/38 (2006.01) C07D 213/64 (2006.01) C07D 213/65 (2006.01) C07D 213/81 (2006.01) C07D 213/83 (2006.01) C07D 241/24 (2006.01) C07D 261/12 (2006.01)

Patent

CA 2561791

Certain non-imidazole heterocyclic compounds of formula (I) are histamine H3 modulators useful in the treatment of histamine H3 receptor mediated diseases, wherein in the A- and B-containing ring, I) A, B1 and B2 are CH; II) A is CH, one of B1 and B2 is N, and the other of B1 and B2 is CH; or III) A is absent, B1 is CH, and B2 is O; L is -C1-4alkylene- or a covalent bond; Q is -(CH2)mO-, -(CH2)nC=C-(where the -O- and -C=C-portions are directly attached to the ring), carbonyl, or thiocarbonyl; m I 2, 3, or 4; n is 1, 2, 3, or 4.

Certains composés hétérocycliques non-imidazole sont des modulateurs d'histamine H3 qui conviennent pour le traitement de maladies induites par le récepteur d'histamine H3.

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