Chlamydia antigens and corresponding dna fragments and uses...

Details Chlamydia antigens and corresponding dna fragments and uses... Chlamydia antigens and corresponding dna fragments and uses...

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 39/118 (2006.01) C07K 14/295 (2006.01) C07K 16/12 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2349504

In summary of this disclosure, the present invention provides a method of nucleic acid, including DNA, immunization of a host, including humans, against disease caused by infection by a strain of Chlamydia, specifically $I(C. pneumoniae), employing a vector, containing a nucleotide sequence encoding an POMP91B precursor protein of a strain of $I(Chlamydia pneumoniae) and a promoter to effect expression of the POMP91B precursor gene in the host. Modifications are possible within the scope of this invention.

L'invention concerne un procédé d'immunisation d'un hôte, basé sur des acides nucléiques, y compris ADN, concernant également des hôtes humains, contre des maladies provoquées par l'infection par une souche de Chlamydia, en particulier, C. pneumoniae, mettant en application un vecteur, contenant une séquence de nucléotides codant un protéine de précurseur de POMP91B d'une souche de Chlamydia pneumoniae et un promoteur servant à effectuer l'expression du précurseur de POMP91B chez l'hôte. L'invention peut également englober des modifications.

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