Targeted modification of chromatin structure

Details Targeted modification of chromatin structure Targeted modification of chromatin structure

C - Chemistry, Metallurgy

12

N

C12N 15/10 (2006.01) C07K 14/47 (2006.01) C07K 14/485 (2006.01) C07K 14/505 (2006.01) C07K 14/705 (2006.01) C07K 14/72 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01) C12N 15/67 (2006.01) C12N 15/82 (2006.01) C12Q 1/68 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2407460

Methods and compositions of targeted modification of chromatin structure, within a region of interest in cellular chromatin, are provided. Such methods and compositions are useful for facilitating processes such as, for example, transcription and recombination, that require access of exogenous molecules to chromosomal DNA sequences.

Procédés et compositions servant à effectuer la modification ciblée d'une structure de chromatine à l'intérieur d'une zone définie de la chromatine cellulaire. Ces procédés et ces compositions sont utiles pour faciliter des processus tels que, par exemple, la transcription et la recombinaison, nécessitant l'accès de molécules exogènes à des séquences d'ADN chromosomiques.

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