Combination of polychitosamine and fibrate for the...

Details Combination of polychitosamine and fibrate for the... Combination of polychitosamine and fibrate for the...

A - Human Necessities

61

K

A61K 31/722 (2006.01) A23L 1/30 (2006.01) A61K 31/216 (2006.01) A61P 3/06 (2006.01)

Patent

CA 2623475

The present invention relates to pharmaceutical compositions comprising a fibrate (e.g. ciprofibrate, gemfibrozil, benzafibrate, and fenofibrate) and a polychitosamine (e.g. chitosan) having molecular weights of less than 650 Kda and degrees of deacetylation of from 70% to 100%. Uses of said compositions for the treatment of hyperlipidemia and associated conditions (e.g. hypercholesterolemia, atherosclerosis, coronary heart disease and cardiovascular disease) or as functional foods are also disclosed.

La présente invention porte sur des compositions pharmaceutiques renfermant un fibrate (tel que le ciprofibrate, le gemfibrozil, le benzafibrate et le fenofibrate) et une polychitosamine (telle que le chitosane) présentant des poids moléculaires inférieurs à 650 Kda et des degrés de désacétylation compris entre 70 et 100 %. Cette invention concerne également des utilisations de ces compositions dans le traitement de l'hyperlipidémie et d'états associés (tels que l'hypercholestérolémie, l'athérosclérose, la coronaropathie et la maladie cardiovasculaire) ou comme aliments fonctionnels.

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