Methods and materials for stabilizing analyte sensors

A - Human Necessities – 61 – B

Patent

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A61B 5/00 (2006.01)

Patent

CA 2658759

The disclosure provides a sensor including a sensor having an external surface and a cannula. The cannula comprises a substantially cylindrical wall encircling a lumen, at least one aperture and a distal end. The sensor is positioned within the lumen and the distal end of the cannula extends beyond the sensor. This configuration functions for example to stabilize chemical reactions associated with the sensor by creating a buffer zone between the sensor and the surrounding tissues at the site of implantation. In certain embodiments, the sensor can further comprise an accessory material in proximity to the external surface, wherein the accessory material modifies the biological response of a tissue that is in contact with the sensor. The sensor can also comprise anchors that keeps the sensor in contact with subcutaneous tissue of a subject upon insertion of the sensor into the body of the subject.

La présente invention concerne un capteur, notamment un capteur ayant une surface externe et une canule. La canule comprend une paroi sensiblement cylindrique encerclant une lumière, au moins une ouverture et une extrémité distale. Le capteur est positionné dans la lumière et l'extrémité distale de la canule s'étend au-delà du capteur. Cette configuration permet, par exemple, de stabiliser des réactions chimiques associées au capteur en créant une zone tampon entre le capteur et les tissus environnants au niveau du site d'implantation. Dans certains modes de réalisation, le capteur peut comprendre, en outre, un matériau accessoire à proximité de la surface externe, le matériau accessoire modifiant la réponse biologique d'un tissu en contact avec le capteur. Le capteur peut également comprendre des ancrages qui maintiennent le capteur en contact avec le tissu sous-cutané d'un sujet lors de l'insertion du capteur dans le corps du sujet.

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