Methods for reduced renal uptake of antibody fragments

Details Methods for reduced renal uptake of antibody fragments Methods for reduced renal uptake of antibody fragments

A - Human Necessities

61

K

A61K 51/10 (2006.01)

Patent

CA 2190867

Kidney uptake of antibody fragment conjugates in patients is reduced by administration to the patient of one or more compounds selected from the group consisting of D-lysine, poly-D-lysine, or poly-L-lysine, or pharmaceutically acceptable salts or carboxyl derivatives thereof.

On réduit chez des patients l'absorption rénale de conjugués de fragments d'anticorps en leur administrant un ou plusieurs composés choisis dans le groupe comprenant D-lysine, poly-D-lysine ou poly-L-lysine, ou des sels ou des dérivés carboxyle de ceux-ci, acceptables sur le plan pharmacologique.

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