A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/12 (2006.01) A61K 9/14 (2006.01) A61K 38/22 (2006.01) A61K 38/26 (2006.01) A61K 38/27 (2006.01) A61K 38/28 (2006.01) A61K 39/29 (2006.01) A61K 47/18 (2006.01) C07K 14/00 (2006.01) C07K 14/475 (2006.01) C07K 14/52 (2006.01) C07K 14/575 (2006.01) C07K 16/00 (2006.01)
Patent
CA 2726230
A dry composition for use in therapy or diagnosis, obtainable by drying an aqueous composition comprising a pro-tein and one or more displacement buffers, such as TRIS, lactate, lysine and histidine wherein the pH of the aqueous composition is such that the protein is stable, wherein the or each displacement buffer has a pKa that is at least 1 unit greater or less than the pH of the aqueous composition, and wherein the aqueous composition is substantially free of a conventional buffer having a pKa that is within one pH unit of the pH of the aqueous composition.
L'invention concerne une composition sèche destinée à être utilisée en thérapie ou diagnostic, que l'on peut obtenir par séchage d'une composition aqueuse comprenant une protéine et un ou plusieurs tampons de déplacement, par exemple TRIS, lactate, lysine et histidine, le pH de la composition aqueuse étant tel que la protéine est stable, chaque tampon de déplacement présentant un pKa qui est supérieur ou inférieur d'au moins une unité au pH de la composition aqueuse, ladite composition étant sensiblement exempte de tampon classique ayant un pKa compris dans une unité pH du pH de la composition aqueuse.
Jezek Jan
Potter Charles
Arecor Limited
Gowling Lafleur Henderson Llp
LandOfFree
The stabilisation of proteins does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with The stabilisation of proteins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and The stabilisation of proteins will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1754428