Blood group antibody screening

Details Blood group antibody screening Blood group antibody screening

G - Physics

01

N

G01N 33/80 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2684112

An assay for the detection of antibodies to blood group antigens, comprises a solid substrate having immobilised thereon a fragment of cell membrane which presents a blood group antigen capable of binding to a blood group antibody. The cell fragments are preferably from red blood cells. Generally, the antigens are immobilised in the form of an array of spots.

La présente invention concerne une analyse pour la détection des anticorps dirigés contre les antigènes des groupes sanguins qui comprend un substrat solide sur lequel est immobilisé un fragment de membrane cellulaire qui présente un antigène des groupes sanguins capable de se lier à un anticorps des groupes sanguins. Les fragments cellulaires sont de préférence des globules rouges. En général, les antigènes sont immobilisés sous la forme d'une série de points.

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