Sustained release of positively charged pharmacologically...

Details Sustained release of positively charged pharmacologically... Sustained release of positively charged pharmacologically...

A - Human Necessities

61

K

A61K 9/70 (2006.01) A61F 13/00 (2006.01)

Patent

CA 2536040

An oral pharmaceutical composition, comprising one or more positively charged, highly water-soluble pharmaceutically active agents such as trospium chloride , and one or more polymers containing polarized oxygen atoms, whereby the active agent(s) form an ion-dipole interaction with the polymer(s) that may be used for an immediate release system, an extended release system or a delayed release system.

L'invention concerne une composition pharmaceutique contenant un ou plusieurs agents actifs d'un point de vue pharmaceutique hautement solubles dans l'eau et positivement chargés, tels que le chlorure de trospium, et un ou plusieurs polymères contenant des atomes d'oxygène polarisés, le ou les agents actifs formant une interaction ion-dipôle avec le ou les polymères pouvant être utilisés dans un système à libération immédiate, un système à libération prolongée, ou un système à libération retardée.

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