Tethered ligands and methods of use

Details Tethered ligands and methods of use Tethered ligands and methods of use

G - Physics

01

N

G01N 33/68 (2006.01) C07K 14/52 (2006.01) C07K 14/715 (2006.01) C12N 15/10 (2006.01) G01N 33/50 (2006.01) G01N 33/531 (2006.01)

Patent

CA 2390690

The invention provides methods, reagents and devices for analysis of receptor ligand interactions, determining the profile of receptor expression in cells and cell populations, and diagnostic and drug screening methods. The invention makes use of immobilized tethered ligand fusion proteins having a ligand domain, a stalk domain, and optionally an immobilization domain.

L'invention se rapporte à des procédés, des réactifs et des dispositifs permettant l'analyse des interactions ligand-récepteur grâce à la détermination du profil d'expression des récepteurs dans des cellules et des populations de cellules, ainsi qu'à des méthodes de diagnostic et de sélection de médicaments. L'invention met en oeuvre des protéines de fusion ligands, captives, immobilisées, présentant un domaine ligand, un domaine pédoncule et éventuellement un domaine d'immobilisation.

Affiliated with

Also associated with

Rating

Tethered ligands and methods of use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tethered ligands and methods of use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tethered ligands and methods of use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1755372