Method for targeted cell ablation

Details Method for targeted cell ablation Method for targeted cell ablation

C - Chemistry, Metallurgy

12

N

C12N 15/09 (2006.01) A01K 67/00 (2006.01) C12N 15/00 (2006.01) C12N 15/63 (2006.01) C12Q 1/00 (2006.01) C12N 15/90 (2006.01)

Patent

CA 2658351

The present technology relates to a method for causing cell death. The method comprises the step of genetically manipulating chromosomal DNA of a cell such as by, for example, using a recombinase system, to lose an autosome during cell division and wherein loss of the autosome results in death of the cell. The technology also relates to a method for selective ablation of proliferative cells within a population of cells.

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