C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 495/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01) C07D 471/04 (2006.01) C07D 491/04 (2006.01)
Patent
CA 2472619
Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
L'invention concerne des composés et des dérivés de ceux-ci, la synthèse et l'utilisation de ceux-ci comme inhibiteurs de la Rho-kinase. Ces composés sont utiles aux fins d'inhibition de croissance tumorale et aux fins de traitement de dysfonction érectile et d'autres indications induites par la Rho-kinase, par exemple, une coronaropathie.
Asgari Davoud
Hart Barry
Khire Uday
Liu Xiao-Gao
Lynch Mark
Bayer Healthcare Ag
Bayer Schering Pharma Aktiengesellschaft
Fetherstonhaugh & Co.
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