Immunological activity of rhamnolipids

Details Immunological activity of rhamnolipids Immunological activity of rhamnolipids

A - Human Necessities

61

K

A61K 31/7028 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01) A61P 31/18 (2006.01) C12P 19/44 (2006.01)

Patent

CA 2195419

Methods for treating various autoimmune diseases and for providing immunorestoration, by administering, to a subject in need thereof, an effective amount of a composition having, as active ingredient, one or more rhamnolipids of formula (I) wherein R1 is H or .alpha.-L-rhamnopyranosyl; R2 is H or -CH(R4)-CH2-COOH; R3 is (C5-C20)-saturated, mono or polyunsaturated hydrocarbyl and R4 is (C5-C20)-saturated, mono or polyunsaturated hydrocarbyl; are provided.

L'invention concerne des procédés pour traiter diverses maladies auto-immunes et pour assurer une immunoreconstitution, en administrant, à un sujet dont l'état le requiert, une quantité efficace d'une composition possédant comme principe actif un ou plusieurs rhamnolipides de formule (I) dans laquelle R<1> est H ou alpha -L-rhamnopyranosyl; R<2> est H ou -CH(R<4>)-CH2-COOH; R<3> est hydrocarbyle saturé, mono ou polyinsaturé en C5-C20 et R<4> est hydrocarbyle saturé, mono ou polyinsaturé en C5-C20.

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