A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/127 (2006.01) A61K 47/24 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2501601
A method of treating insulin resistance, adult onset diabetes, and metabolic syndrome X and its related complications, in a mammalian subject is accomplished by intravenously administering to a mammalian subject, a therapeutically effective amount of a liposomal suspension of lipoprotein small unilamellar vesicles (SUVs) comprising predominantly phospholipids. The liposomal suspension is administered over a period of time, whereby in the levels of some or all of blood glucose, insulin, total cholesterol, LDL cholesterol, triglyceride, creatine kinase (CK), creatine kinase-MB (CK-MB), Hb-A1c, lipoprotein (a), SGOT and SGPT fall back within the normal range or are significantly reduced.
L'invention concerne un procédé de traitement de la résistance à l'insuline, du diabète chez l'adulte, et du syndrome X métabolique ainsi que les complications associées, chez un mammifère. Ce procédé consiste à administrer par voie intraveineuse, à un mammifère, un quantité thérapeutiquement efficace d'une suspension liposomale de petits liposomes unilamellaires (SUV) de lipoprotéine contenant en majorité des phospholipides. Cette suspension liposomale est administrée pendant un certain temps, si bien que tous les niveaux ou certains des niveaux de glycémie, insuline, cholestérol total, cholestérol LDL, triglycéride, créatine kinase (CK), créatine kinase-MB (CK-MB), Hb-A1c, lipoprotéine (a), SGOT et SGPT ont une valeur normale ou sont significativement réduits.
Kurtz Seymour J.
Moffat & Co.
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