Multiparameter facs assays to detect alterations in cellular...

G - Physics – 01 – N

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G01N 33/50 (2006.01) G01N 33/533 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2325597

The invention relates to novel methods of detecting alterations in cell cycle regulation in a cell or a cell population and screening for agents capable of modulating cell cycle regulation through the use of multiparameter assays and a fluorescence-activated cell sorter (FACS) machine.

Dans la présente invention, on divulgue de nouvelles méthodes de détection des modifications de la régulation du cycle cellulaire d'une cellule ou d'une population de cellules et de criblage d'agents pouvant moduler la régulation du cycle cellulaire, au moyen d'épreuves multiparamétriques et d'un appareil de triage de cellules activé par fluorescence.

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