Amidopropoxyphenyl orexin receptor antagonists

Details Amidopropoxyphenyl orexin receptor antagonists Amidopropoxyphenyl orexin receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 277/56 (2006.01)

Patent

CA 2603766

The present invention is directed to amidopropoxyphenyl compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.

La présente invention a pour objet des composés de type amidopropoxyphényle qui sont des antagonistes des récepteurs de l'orexine, et qui peuvent être employés dans le traitement prophylactique ou thérapeutique de troubles neurologiques et psychiatriques et de maladies dans lesquelles interviennent les récepteurs de l'orexine. La présente invention concerne également des préparations pharmaceutiques comprenant lesdits composés, ainsi que l'emploi desdits composés et préparations dans le traitement prophylactique ou thérapeutique de maladies dans lesquelles interviennent les récepteurs de l'orexine.

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