A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/48 (2006.01) A01N 37/36 (2006.01) A61K 39/395 (2006.01)
Patent
CA 2293429
The present invention provides a method of treatment for patients with a variety of thrombotic disorders including, but not limited to, stroke, venous thrombosis, myocardial infarction, unstable angina, abrupt closure following angioplasty or stent placement, and thrombosis as a result of peripheral vascular surgery. Said treatment is a combination therapy with human aPC and antiplatelet agents including, but not limited to, aspirin (ASA), clopidogrel, ReoPro (abciximab), dipyridamole, ticlopidine and IIb/IIIa receptor antagonists. The synergy will result in the ability to reduce the dosages of the agents used in the combination therapy.
L'invention porte sur un procédé de traitement de patients souffrant de différents troubles thrombotiques dont, non limitativement, les attaques, les thromboses veineuses, les infarctus du myocarde, l'angor instable, les obturations soudaines suivant une angioplastie ou la mise en place d'une prothèse endovasculaire, ou une thrombose consécutive à une opération sur le système vasculaire périphérique. Ledit traitement est une thérapie combinée d'aPC et d'antiplaquetaires dont, non limitativement: l'aspirine, le clopidogrel, le ReoPro? (abciximab), la ticlopidine et les antagonistes des récepteurs IIb/IIIa. Cette synergie permet de réduire les dosages des différents agents utilisés dans la thérapie combinée.
Grinnell Brian William
Jakubowski Joseph Anthony
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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