Whitening compositions containing ascomycete derived enzyme

A - Human Necessities – 61 – K

Patent

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Details

A61K 8/66 (2006.01) A61K 8/97 (2006.01) A61K 36/06 (2006.01) A61K 38/43 (2006.01) A61Q 19/02 (2006.01)

Patent

CA 2406202

The present invention relates to topical whitening compositions comprising a whitening effective amount of an Ascomycete-derived melanin-degrading enzyme extract and methods of preparing the composition. The composition provide a whitening effect which occurs by degrading melanin in the skin, yet the compositions themselves do not turn dark in color. The enzyme extract can be derived from Aspergillus fumigatus or Saccharomyces cerevisiae, and is added to the compositions of the present invention. The compositions containing the enzyme extract are twice as effective as kojic acid in producing a whitening effect on the skin.

L'invention concerne des compositions topiques éclaircissantes qui contiennent une quantité efficace d'extrait d'une enzyme dégradant la mélanine dérivée d'ascomycète, et des procédés de préparation de cette composition. Ces compositions ont un effet éclaircissant, produit par une dégradation de la mélanine contenue dans la peau ; par ailleurs les compositions elles-mêmes ne foncent pas. L'extrait d'enzyme peut être dérivé d'Aspergillus fumigatus ou de Saccharomyces cerevisiae, et est ajouté aux compositions de l'invention. Les compositions qui contiennent cet extrait d'enzyme sont deux fois plus efficaces que l'acide kojique du point de vue de leur effet éclaircissant sur la peau.

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