Piperidine derivatives as ccr5 inhibitors

Details Piperidine derivatives as ccr5 inhibitors Piperidine derivatives as ccr5 inhibitors

C - Chemistry, Metallurgy

07

D

C07D 417/14 (2006.01) A61K 31/4427 (2006.01) A61K 31/4545 (2006.01) C07D 211/58 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2501243

Disclosed are compounds of formula (I) wherein R1, R2, R3 and X are as defined herein, in free or salt form, which are useful as CCR5 inhibitors, e.g. in the prevention or treatment of disorders mediated by interactions between chemokine receptors and their ligands.

L'invention porte sur des composés de formule (I) (sous forme libre ou de sels), dans laquelle: R¿1?, R¿2?, R¿3? et X sont tels que définis dans la description, et utilisables comme inhibiteurs du CCR5, et notamment pour la prévention ou le traitement de troubles médiés par des interactions entre les récepteurs de la chémokine et leurs ligands.

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