Immune-evading proteins

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/62 (2006.01) A61K 31/70 (2006.01) A61K 38/16 (2006.01) A61K 39/245 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C07K 14/05 (2006.01) C07K 19/00 (2006.01) C12N 15/38 (2006.01) G01N 33/554 (2006.01)

Patent

CA 2217977

The invention provides compositions and methods for preventing undesired immune responses in which a recombinant protein is prepared which includes a glycine-containing amino acid sequence, the glycine-containing sequence conferring upon the recombinant protein substantial invisibility to the immune system.

L'invention porte sur des compositions et méthodes de prévention des réponses immunitaires non désirées consistant à intégrer auxdites compositions une protéine de recombinaison comportant une séquence aminoacide contenant de la glycine qui lui confère une quasi invisibilité vis à vis du système immunitaire.

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