T-type voltage-gated calcium channels and method of using same

Details T-type voltage-gated calcium channels and method of using same T-type voltage-gated calcium channels and method of using same

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2312477

The present invention provides an isolated or substantially purified nucleic acid encoding a protein comprising at least one domain of a T-type calcium channel and cells and cell lines expressing such nucleic acids. The present invention also provides an isolated or substantially purified T-type calcium channel and an isolated or substantially purified antibody molecule recognizing an epitope on a T-type calcium channel protein.

La présente invention concerne un acide nucléique isolé ou sensiblement purifié codant une protéine comprenant au moins un domaine d'un canal calcique de type T, ainsi que des cellules et des lignées cellulaires exprimant ces acides nucléiques. La présente invention concerne également un canal calcique de type T isolé ou sensiblement purifié et une molécule anticorps isolée ou sensiblement purifiée reconnaissant un épitope sur une protéine de canal calcique de type T.

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