Agent for inhibiting the formation of denatured ldl

Details Agent for inhibiting the formation of denatured ldl Agent for inhibiting the formation of denatured ldl

A - Human Necessities

61

K

A61K 31/10 (2006.01) A61K 31/12 (2006.01) A61K 31/135 (2006.01) A61K 31/155 (2006.01) A61K 31/16 (2006.01) A61K 31/165 (2006.01) A61K 31/17 (2006.01) A61K 31/18 (2006.01) A61K 31/185 (2006.01) A61K 31/19 (2006.01) A61K 31/195 (2006.01) A61K 31/215 (2006.01) A61K 31/22 (2006.01) A61K 31/275 (2006.01) A61K 31/335 (2006.01) A61K 31/34 (2006.01) A61K 31/35 (2006.01) A61K 31/36 (2006.01) A61K 31/38 (2006.01) A61K 31/40 (2006.01) A61K 31/415 (2006.01) A61K 31/42 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01)

Patent

CA 2076012

-101- ABSTRACT OF THE DISCLOSURE The compounds of the present invention effectively suppress the negative charge of LDL (Low Density Lipoprotein). Namely, these compounds, which suppress the denaturation (oxidation) required in the recognition of LDL y scavenger receptors, are available as a remedy for arteriosclerosis peptic ulcers, cancer, ischemic organo- pathy, inflammation and pulmonary diseases caused by, for example, silicon dust. The effect of suppressing the negative charge of LDL can be confirmed by agarose gel electrophoresis.

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