Eotaxin: eosinophil chemotactic cytokine

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/19 (2006.01) A61K 38/19 (2006.01) A61K 39/395 (2006.01) C07K 14/52 (2006.01) C07K 14/715 (2006.01) C07K 16/24 (2006.01) C07K 16/28 (2006.01) C12P 21/02 (2006.01) G01N 33/15 (2006.01) G01N 33/48 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2171761

A chemoattractant protein called "eotaxin" is capable of attracting eosinophils and of inducing eosinophil accumulation and/or activation in vitro and in vivo. Various types of agents that inhibit or otherwise hinder the production, release or activity of eotaxin may be used therapeutically in the treatment of asthma and other inflammatory diseases.

Une protéine chimiotactique appelée "éotaxine" est capable d'attirer les éosinophiles et de provoquer leur accumulation et/ou leur activation in vitro et in vivo. On peut utiliser divers types d'agents qui inhibent ou empêchent d'une autre manière la production, la libération ou l'activité de l'éotaxine, dans le traitement de l'asthme et d'autres états inflammatoires.

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