Medical devices and materials containing isobutylene copolymer

Details Medical devices and materials containing isobutylene copolymer Medical devices and materials containing isobutylene copolymer

C - Chemistry, Metallurgy

08

L

C08L 23/22 (2006.01) A61L 27/34 (2006.01) C08L 25/10 (2006.01)

Patent

CA 2574489

The present invention relates to medical devices which contain isobutylene copolymers. The present invention also relates to biocompatible copolymer materials for therapeutic agent delivery comprising a therapeutic-agent-loaded isobutylene copolymer. According to an aspect of the present invention, a medical device is provided, which includes: (a) a substrate and (b) at least one polymeric layer, which contains a copolymer, disposed over all or a portion of the substrate. The copolymer contains one or more polymer chains, within which isobutylene and elevated Tg monomers (and, optionally, other monomers) are incorporated in a random, periodic, statistical or gradient distribution.

Cette invention concerne des dispositifs médicaux qui contiennent des copolymères d'isobutylène. Cette invention concerne également des matériaux à base de copolymère biocompatible pour la libération d'agents thérapeutiques, comprenant un copolymère d'isobutylène chargé d'agent thérapeutique. Conformément à l'un de ses aspects, cette invention propose un dispositif médical, qui comprend: (a) un substrat et (b) au moins une couche polymère, qui contient un copolymère, disposée sur la totalité ou une partie du substrat. Ce copolymère contient une ou plusieurs chaînes polymères, dans lesquelles de l'isobutyléne et des monomères Tg élevés (et éventuellement d'autres monomères) sont incorporés selon une distribution aléatoire, périodique, statistique ou gradiente.

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