Novel sulfamides and their use as endothelin receptor...

C - Chemistry – Metallurgy – 07 – D

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C07D 239/46 (2006.01) A61K 31/506 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2431675

The invention relates to novel sulfamides of general formula (I) and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as endothelin receptor antagonists.

L'invention porte sur de nouveaux sulfamides de la formule générale (I) et sur leur utilisation comme ingrédients actifs dans la préparation de compositions pharmaceutiques. L'invention porte également sur les procédés de préparation de composés, des compositions pharmaceutiques contenant un ou plusieurs de ces composés et notamment sur leur utilisation comme antagonistes du récepteur de l'endothéline.

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