G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/68 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2580532
Methods and compositions relating to Alzheimer's disease are provided. Specifically, proteins that are differentially expressed in the Alzheimer's disease state relative to their expression in the normal state are provided. Proteins associated with Alzheimer's disease are identified and described. Methods of diagnosis of Alzheimer's disease using the differentially expressed proteins are also provided, as are methods for the identification and therapeutic use of compounds for the prevention and treatment of Alzheimer's disease.
La présente invention se rapporte à des procédés et à des compositions liées à la maladie d'Alzheimer. L'invention concerne en particulier des protéines dont l'expression n'est pas identique dans l'état lié à la maladie d'Alzheimer et dans l'état normal. Des protéines associées à la maladie d'Alzheimer sont identifiées et décrites. L'invention concerne également des procédés permettant de diagnostiquer la maladie d'Alzheimer à l'aide des protéines exprimées différemment, ainsi que des procédés d'identification et d'utilisation thérapeutique de composés destinés à prévenir et à traiter la maladie d'Alzheimer.
Baumann Christian
Byers Helen
Hye Abdul
Joubert Richard
Kienle Stefan
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
King's College London
Proteome Sciences Plc
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