An isolated polynucleotide associated with type ii diabetes...

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 21/04 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2465192

The present invention provides isolated polynucleotides that include sequences from a region of human chromosome 20q between D20S119 and D20S195. The polynucleotides include polymorphisms associated with Type II diabetes and are useful as probes in screening for Type II diabetes. The invention further provides methods of detecting polymorphisms on chromosome 20q between D20S119 and D20S195, and methods of detecting a propensity to develop Type II diabetes, using the isolated polynucleotides of the invention.

L'invention concerne des polynucléotides isolés comportant des séquences d'une région du chromosome humain 20q entre D20S119 et D20S195. Ces polynucléotides comprennent des polymorphismes associés au diabète sucré de type II et sont utiles en tant que sondes de criblage pour ce type de diabètes. L'invention concerne aussi des procédés de détection de polymorphismes sur le chromosome 20q entre D20S119 et D20S195, ainsi que des procédés de détection d'une propension à développer des diabètes de type II, au moyen des polynucléotides de l'invention.

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