Conjugates of photosensitisers and antibodies

Details Conjugates of photosensitisers and antibodies Conjugates of photosensitisers and antibodies

A - Human Necessities

61

K

A61K 47/00 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01)

Patent

CA 2624841

The invention provides a compound comprising a photosensitising agent coupled to a carrier molecule with a minimum coupling ratio of 3 :1 wherein the carrier molecule has a binding specificity for a target cell. There is also provided a process of conjugation comprising the use of a first and second aprotic solvent and uses of the conjugated compounds.

L'invention concerne un composé comprenant un agent photosensibilisant couplé à une molécule support selon un rapport de couplage minimum de 3:1; la molécule support présentant une spécificité de liaison à une cellule cible. L'invention concerne également un procédé de conjugaison faisant intervenir un premier et un deuxième solvant aprotique ainsi que l'utilisation des composés conjugués.

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