Polypeptides and nucleic acids encoding these and their use...

Details Polypeptides and nucleic acids encoding these and their use... Polypeptides and nucleic acids encoding these and their use...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 31/7088 (2006.01) A61K 31/7105 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C07H 21/02 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) G01N 33/48 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2494899

The invention relates to polypeptides and nucleic acids encoding these and to their use for the diagnosis, prevention and/or treatment of liver disorders and neoplastic disorders, especially cancer of the liver and other epithelial tissues, benign liver neoplasms such as adenoma and other proliferative liver disorders such as focal nodular hyperplasia (FNH) and cirrhosis. The invention further relates to methods of diagnosing and treating these disorders.

L'invention concerne des polypeptides et des acides nucléiques codant ceux-ci et l'utilisation de ceux-ci pour le diagnostic, la prévention et/ou le traitement de troubles du foie et néoplastiques, notamment le cancer du foie et d'autres tissus épithéliaux, de néoplasmes bénins du foie, tels que l'adénome et d'autres troubles prolifératifs du foie, tels que l'hyperplasie nodulaire focale (FNH) et la cirrhose. L'invention concerne enfin des procédés de diagnostic et de traitement de ces troubles.

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