A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 35/12 (2006.01) A61K 31/575 (2006.01) A61K 35/54 (2006.01) C07J 9/00 (2006.01) C12N 9/02 (2006.01)
Patent
CA 2191467
The present invention provides a substantially purified cellular factor that can regulate the expression of genes that encode proteins involved in cholesterol metabolism. The invention also provides methods of obtaining the cellular factors of the invention in a substantially purified form. The invention further provides a method of using a cellular factor of the invention to reduce cholesterol levels in a subject having hypercholesterolemia comprising administering a cellular factor to the subject.
La présente invention a pour objet un facteur cellulaire sensiblement purifié régulant l'expression de gènes codant les protéines impliquées dans le métabolisme du cholestérol. L'invention a également pour objet des méthodes permettant d'obtenir lesdits facteurs cellulaires sous une forme sensiblement purifiée. L'invention concerne en outre une méthode d'utilisation dudit facteur cellulaire afin de réduire les taux de cholestérol chez un sujet atteint d'hypercholestérolémie, ladite méthode consistant à administrer un facteur cellulaire au sujet.
Gowling Lafleur Henderson Llp
San Diego State University Foundation
LandOfFree
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