Polyamine analogues as cytotoxic agents

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 211/27 (2006.01) A61K 31/135 (2006.01) A61K 31/33 (2006.01) C07C 211/30 (2006.01) C07C 211/31 (2006.01) C07C 211/49 (2006.01) C07C 211/54 (2006.01) C07C 217/40 (2006.01) C07C 217/58 (2006.01) C07C 223/02 (2006.01) C07C 233/37 (2006.01) C07C 233/40 (2006.01) C07C 233/62 (2006.01) C07C 237/10 (2006.01) C07C 247/16 (2006.01) C07C 279/12 (2006.01) C07C 311/19 (2006.01) C07C 311/39 (2006.01) C07C 317/44 (2006.01) C07D 207/16 (2006.01) C07D 209/18 (2006.01) C07D 213/36 (2006.01) C07D 213/38 (2006.01) C07D 21

Patent

CA 2403814

Novel cytotoxic polyamine analogues are disclosed. These analogues are useful pharmaceutical agents for treating diseases where it is desired to inhibit cell growth and/or proliferation, for example cancer and post-angioplasty injury.

L'invention porte sur de nouveaux analogues cytotoxiques de la polyamine utilisables comme agents pharmaceutiques pour le traitement de maladies requérant l'inhibition de la croissance et/ou de la prolifération de cellules, telles que par exemple le cancer ou les lésions post-angioplastiques.

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