Crig antagonists

Details Crig antagonists Crig antagonists

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01)

Patent

CA 2682835

The present invention concerns blocking antibodies specifically binding a recently discovered macrophage specific receptor, CRIg, and their use to prevent cellular entry of intracellular pathogens, such as viruses, bacteria or parasites as well as for prevention of unwanted clearance of erythrocytes and platelets.

L'invention concerne le blocage d'anticorps se liant spécifiquement un récepteur spécifique de macrophage récemment découvert, CRIg, et leur utilisation pour empêcher l'entrée cellulaire de pathogènes intracellulaires, tels que des virus, des bactéries ou des parasites, de même que pour la prévention du dégagement non souhaité des érythrocytes et des plaquettes.

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