Method for detection of a physiological abnormality

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/02 (2006.01) G01N 33/50 (2006.01) G01N 33/60 (2006.01)

Patent

CA 2089486

2089486 9203573 PCTABS00011 The present invention relates to an assay method for detecting a physiological abnormality in a human or animal. The invention is particularly described in relation to human hypertension (high blood pressure) in an adult study group and as a predictive marker for hypertension in an adolescent study group. In a particular embodiment there is described the use of human cheek epithelial cells to measure sodium ion (Na+) transport using radiolabelled 22Na+. Also disclosed is the use of cheek cell Na+ transport activity as a predictive marker for hypertension.

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