Thiazolyl-substituted quinolylmethoxyphenylacetic acid...

C - Chemistry – Metallurgy – 07 – D

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C07D 417/12 (2006.01) A61K 31/47 (2006.01) C07D 215/14 (2006.01) C07D 401/12 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2084131

Thiazolyl-substituted quinolylmethoxyphenylacetic acid derivatives A b s t r a c t Thiazolyl-substituted quinolylmethoxyphenylacetic acid derivatives are prepared by reaction of halogenoaceto- acetic acid esters with quinolylmethoxyphenylacetic acid thioamides, which are obtainable from corresponding amides with Lawesson's reagent The substances can be employed in medicaments as inhibitors of enzymatic reactions in the context of arachidonic acid metabolism. Le A 28 661 - US

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