C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/38 (2006.01) A61K 31/557 (2006.01) A61K 31/66 (2006.01) A61K 31/695 (2006.01) A61K 51/04 (2006.01) C07C 405/00 (2006.01) C07D 309/12 (2006.01) C07F 7/08 (2006.01) C07F 7/18 (2006.01) C07F 9/553 (2006.01) C07F 9/572 (2006.01)
Patent
CA 2144093
This invention relates to a prostaglandin-bisphosphonate compound of formula (I) and its pharmaceutically acceptable salts. The claimed compounds are effective as delivery agents of prostaglandins to treat osteoporosis and related bone diseases. The claimed compounds also simultaneously deliver a bisphosphonate which inhibits bone resorption and delivers prostaglan- dins which increase bone formation in vivo.
Rodan Gideon A.
Ruel Rejean
Tyler Peter C.
Young Robert N.
Merck & Co. Inc.
Merck Frosst Canada Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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