C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
260/576, 260/580
C07C 45/56 (2006.01) C07C 49/17 (2006.01) C07C 49/245 (2006.01)
Patent
CA 2006340
ABSTRACT OF THE INVENTION A process for the preparation of .beta.-hydroxyketones comprising the catalytic hydrogenolysis of an aqueous solution of isoxazolines having the formula Image in a fixed bed reactor containing a transition metal catalyst at a temperature between 20 to 150°C and a pressure from about 0 to 150 psig; wherein R1 and R2 are independently selected from hydrogen, alkyl, cycloalkyl or aromatic group and wherein the aqueous solution of isoxazolines is substantially free of acids or buffers.
Kloczewski Harold
Lin You-Jyh
Gowling Lafleur Henderson Llp
W.r. Grace & Co.,-Conn.
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