A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/195 (2006.01) A61K 31/198 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2542661
Pharmaceutical compositions and kits useful for the treatment of cancer include certain alkyl esters of cystine and certain alkyl-substituted cystamine derived esters, including, for example, cystine dimethyl ester and a di-alkyl peptidyl cystamine ester, among others. These compounds may be employed in methods of treating cancers or methods of determining sensitivity of certain cancer cells to apoptosis alone, or in combination with other chemotherapeutic, radiological or apoptotic agents.
La présente invention concerne des compositions pharmaceutiques et des trousses utilisées dans le traitement du cancer, lesquelles compositions contiennent certains alkyl esters de la cystine et certains esters dérivés de la cystamine substitués par alkyle, y compris, par exemple, un ester de cystine diméthyle et un ester de di-alkyl peptidyl cystamine, entre autres. Les composés précités peuvent être utilisés selon des procédés permettant de traiter le cancer ou permettant de déterminer la sensibilité de certaines cellules cancéreuses à l'apoptose, seuls ou combinés à d'autres agents chimiothérapeutiques, radiologiques ou apoptotiques.
Gowling Lafleur Henderson Llp
The Administrators Of The Tulane Educational Fund
LandOfFree
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