Hepatitis a virus strain, method for the isolation of new...

C - Chemistry – Metallurgy – 12 – N

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C12N 7/01 (2006.01) A61K 39/29 (2006.01) A61K 39/42 (2006.01) C07H 21/02 (2006.01) C07K 14/10 (2006.01) C07K 16/10 (2006.01) C12N 7/02 (2006.01) C12N 7/04 (2006.01) C12P 21/08 (2006.01) G01N 33/576 (2006.01) G01N 33/577 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2086832

The invention relates to hepatitis A-viruses (HAVs) having a serotype displaying the immunological characteristics of the HAV strain RG-SB XA112 (CNCM I-1080). In particular, the invention relates to the new hepatitis A virus strain RG-SB XA112 (CNCM I-1080). The invention also relates to structural components of said HAVs. Furthermore, the invention relates to processes for the isolation of said HAVs. The HAVs of the present invention and the structural components thereof can be used for the production of vaccines and diagnostic compositions. Finally, the invention relates to polyclonal and monoclonal antibodies which are directed to said new HAVs.

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