Polymeric bio-erodible delivery system for the periodontal...

A - Human Necessities – 61 – K

Patent

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A61K 9/70 (2006.01) A61K 9/00 (2006.01) A61K 9/22 (2006.01) A61K 7/16 (1990.01)

Patent

CA 2111136

Abstract A periodontal dosage form and method for delivery of a drug ingredient into a periodontal pocket. It is comprised of a drug containing layer having top and bottom surfaces, and side edges around its periphery where the side edges are substantially free of applied coverings. Directly on the top and bottom surfaces of the drug containing layer are polymeric layers comprising a physiologically acceptable, bio-erodible polymer composition capable of diffusing a drug through it from the drug containing layer when the dosage form is positioned in a periodontal pocket. In use, the patient receives an initial dosage via the side edges of the drug containing layer. Prolonged administration is achieved through slow diffusion through the polymeric covering layers.

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