C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/25 (2006.01) C07K 14/545 (2006.01)
Patent
CA 2378954
The present invention relates to the discovery of novel genes encoded by the interleukin-1 locus. The IL-1L1 gene is located in the interval between the IL- 1Beta and IL-1 receptor antagonist encoding genes and encodes a polypeptide which is homologous to both IL-1 agonist and IL-1 antagonist proteins. Therapeutics, diagnostics and screening assays based on these molecules are also disclosed.
La présente invention concerne la découverte de nouveaux gènes codés par un locus d'interleukine-1. Le gène IL-1L1 est placé dans l'intervalle situé entre les gènes codant l'antagoniste de récepteur IL-1 .beta. et IL-1 et code un polypeptide qui est homologue aux protéines d'antagoniste IL-1 et d'agoniste IL-1. L'invention traite de procédés de dosage, de procédés diagnostiques et thérapeutiques utilisant ces molécules.
Barton Jenny
Nicklin Martin
Barton Jenny
Borden Ladner Gervais Llp
Interleukin Genetics Inc.
Nicklin Martin
LandOfFree
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