Process for preparing phenoxyphenylsulfonyl halides

Details Process for preparing phenoxyphenylsulfonyl halides Process for preparing phenoxyphenylsulfonyl halides

C - Chemistry, Metallurgy

07

C

C07C 309/87 (2006.01) C07C 303/02 (2006.01) C07C 303/22 (2006.01) C07C 303/28 (2006.01) C07C 303/32 (2006.01) C07C 309/42 (2006.01) C07C 309/75 (2006.01)

Patent

CA 2268679

A progress for preparing phenoxyphenylsulfonyl halides of the general formula I: Image wherein R1 is halo and R2 is fluoro, chloro, bromo, alkyl, alkoxy or perfluoroalkyl, which are useful intermediates for the preparation of matrix metalloproteinase inhibitors. The invention also relates to intermediates, useful in the process of the invention, of the general formulas IIa and III: Image wherein R is H, Li, Na, K, Mg or NH4, and Image wherein m is an integer Pram 1 to 3 and R2 is as defined above.

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