C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/39 (2006.01) A61K 38/48 (2006.01) C07K 14/78 (2006.01) C07K 16/18 (2006.01)
Patent
CA 2235393
An inhibitor of endothelial cell proliferation, capable of inhibiting angiogenesis and causing tumor regression, that is approximately 20 kDa and corresponds to a C--terminal fragment of collagen type XVIII and methods of treating angiogenesis-related disease.
L'invention concerne un inhibiteur de la prolifération des cellules endothéliales, capable d'inhiber l'angiogenèse et de provoquer une régression des tumeurs. Cet inhibiteur est d'environ 20 kDa et il correspond à un fragment C-terminal du collagène de type XVIII. L'invention concerne également des thérapies permettant de traiter des maladies liées à l'angiogénèse.
Folkman M. Judah
O'reilly Michael S.
Finlayson & Singlehurst
The Children's Medical Center Corporation
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